Two gunmen on a motorcycle intercepted a taxi on Shahrah-i-Iqbal and opened fire at it, killing driver Shukrullah, 19, and passenger Ramzan Ali, 18.
Rescuers took the bodies and the injured to the Civil Hospital. The wounded, reported to be in critical condition, were later referred to the Combined Military Hospital because of lack of needed facilities at the Civil Hospital.
The scene of the incident was cordoned off by the law-enforcement agencies.
The taxi came under attack at a place where hundreds of people were busy shopping at markets.
A large number of the members of the Shia Hazara community have died in bomb blasts and targeted killings recently.
There was no immediate claim of responsibility. Lashkar-e-Jhangvi, a militant group officially banned by the government in 2002, usually claims responsibility for such attacks.
In January at least 81 people, mainly Shia Muslims, were killed in a bomb attack in the lawless city.
Human Rights Watch says hundreds of Shias were killed in Pakistan in 2012, which was the deadliest year on record for the Shia Muslim community.
Shias make up about a third of Pakistan’s population of over 180 million.
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